AmyloGraph is a database of interactions between amyloid proteins. Curators of AmyloGraph manually gather data from the the published research literature and community data submissions. To learn more about AmyloGraph, its usage and the process of data curation, visit our online manual.
AmyloGraph is available as an online database http://AmyloGraph.com/, but its functionalities are also accessible as this R package.
Run AmyloGraph locally
You can install the development version from GitHub with:
# install.packages("devtools")
devtools::install_github("KotulskaLab/AmyloGraph")
# then run AmyloGraph using
library(AmyloGraph)
AmyloGraph()Frequently asked questions
How can I submit my own data?
The submission form is available online.
Why interactions reported in my publications are wrongly annotated?
We try our best by implementing a rigorous and transparent two-step data curation procedure, but despite these measures, we are still prone to errors. Please send an email to Michal Burdukiewicz with correctly annotated interactions. Remember to mention their AmyloGraph IDs.
Citation
Burdukiewicz M, Rafacz D, Barbach A, Hubicka K, Bakala L, Lassota A, Stecko J, Szymanska N, Wojciechowski J, Kozakiewicz D, Szulc N, Chilimoniuk J, Jeskowiak I, Gasior-Glogowska M, Kotulska M (2022). AmyloGraph: A comprehensive database of amyloid-amyloid interactions. Nucleic Acid Research, 10.1093/nar/gkac882.
Contact
For general questions or problems with the data or database, please email Michal Burdukiewicz.
Acknowledgements
AmyloGraph is partially supported by the grant no. 2019/35/B/NZ2/03997 (National Science Center) to Małgorzata Kotulska. Access to Wroclaw Centre for Networking and Supercomputing at Wroclaw University of Science and Technology is greatly acknowledged. We also thank Daniel Otzen (Aarhus University, Denmark) and Vytautas Smirnovas (University of Vilnus, Lithuania) for fruitful discussions.
